DAY 1: Thursday, March 26, 2026
| Time | Topic | Speaker |
| Introduction | ||
| 8:00 AM | Welcoming remarks |
|
| 8:10 AM | Nuclear medicine in prostate cancer care | Johannes Czernin, MD UCLA |
| PSMA PET | ||
| 8:20 AM | The problem with our reports | Robert Reiter, MD UCLA |
| 8:30 AM | SPECT versus PET: Optimizing response biomarkers | Lisa Bodei, MD, PhD Memorial Sloan Kettering, New York, NY |
| 8:40 AM | Does what we see on PSMA PET matter? | Peter Choyke, MD National Cancer Institute, Bethesda, MD |
| 8:50 AM | Discussion | |
| Clinical Trial Updates | ||
| 9:10 AM | PSMAaddition | Oliver Sartor, MD East Jefferson General Hospital (EJGH) Cancer Center, New Orleans, LA |
| 9:20 AM | DORA and PEACE-3: Evolving role of Ra-223 | Michael Morris, MD Memorial Sloan Kettering, New York, NY |
| 9:30 AM | PEACE-6 | Désirée Deandreis, MD Gustave Roussy, Villejuif, France |
| 9:40 AM | Chemo versus PSMA RLT | François Bénard, MD BC Cancer Research Institute, Vancouver, BC |
| 9:50 AM | STAMPEDE | Nick James, MBBS, PhD Institute of Cancer Research, London, UK |
| 10:00 AM | Discussion | |
| 10:20 AM | BREAK | |
| New Radioligands and Radionuclides | ||
| 10:50 AM | Is Astatine the way to go? | Tadashi Watabe, MD, PhD Osaka University, Japan |
| 11:00 AM | Ac-PSMA: The truth should be told! | Matthias Eiber, MD, PhD Technische Universität München, Germany |
| 11:10 AM | Does dose rate matter? | Amanda Walker AstraZeneca |
| 11:20 AM | Discussion | |
| Market and Raw Materials | ||
| 11:40 AM | The theranostic revolution: Innovation, investment, and implications | Germo Gericke, MD Ariceum Therapeutics, Berlin, Germany |
| 11:50 AM | Raw material supply | Nicolas Mario NucAdvisor, Paris, France |
| 12:00 PM | How we get to the radionuclide | Jon Engle, PhD University of Wisconsin,Madison |
| 12:10 PM | Discussion | |
| 12:30 PM | LUNCH | |
| Approaches to Combination Therapies | ||
| 1:30 PM | PSMA upfront versus RLT at the end | Pending |
| 1:40 PM | Are alpha or beta particles better for immunogenic priming? | Zachary Morris, MD, PhD University of Wisconsin, Madison |
| 1:50 PM | How important is the bystander effect in RLT? | Jean Pierre Pouget, PhD French National Institute for Health and Medical Research |
| 2:00 PM | Immunotherapy beyond checkpoint inhibitors | Lawrence Fong, MD Fred Hutchinson Cancer Center, Seattle, WA |
| 2:10 PM | Discussion | |
| Radiation Sensitivity | ||
| 2:30 PM | Non-PARP DNA repair enzymes: What are the optimal combinations? | Jonathan Chou, MD, PhD UCSF |
| 2:40 PM | Does dosimetry matter? | Pending |
| 2:50 PM | Tests that predict radiation sensitivity: Experience from space travel | Kevin Tabury, PhD Belgian Nuclear Research Center (SCK CEN) |
| 3:00 PM | Mechanisms of resistance to radioligand therapy | Christine Mona, PhD UCLA |
| 3:10 PM | Predicting radiation resistence with ctDNA | Pending |
| 3:20 PM | Discussion | |
| Keynote | ||
| 3:40 PM | Fundamental questions, transformative answers: Driving prostate cancer therapies through basic science | Owen Witte, MD UCLA |
| 4:00 PM | Cocktail hour |
DAY 2: Friday, March 27, 2026
| Time | Topic | Speaker |
| Targeting the Cell Surface | ||
| 8:00 AM | Modalities for targeting the cell surface | Aditya Bardia, MD, MPH UCLA |
| 8:10 AM | ADCs and BiTEs and their role in prostate cancer | Tanya B. Dorff, MD City of Hope, Los Angeles, CA |
| 8:20 AM | DLL3: Does target expression determine the method of targeting? | Rahul Aggarwal, MD UCSF |
| 8:30 AM | Discussion | |
| 8:50 AM | BREAK | |
| Challenges of Radioligand Therapy | ||
| 9:20 AM | The expanding theranostic dream: From hype to hard truths | Michael Hofman, MBBS Peter MacCallum Cancer Centre, Melbourne, Australia |
| 9:35 AM | Renal toxicity associated with PSMA targeted therapy | Inès Camille Azrour, PharmD UCLA |
| 9:45 AM | Long term marrow toxicity: Rates and risk factors | Daniel (Dan) Childs, MD Mayo Clinic, Rochester, MN |
| Radioligand Therapy Tumor Board | ||
| 9:55 AM | Tumor board | |
| 10:55 AM | LUNCH | |
| Clinical Development | ||
| 11:55 AM | Regulatory considerations related to PSMA PET imaging in clinical trials | William Maguire, MD U.S. Food and Drug Administration |
| 12:10 PM | Incorporating PSMA PETs in registrational trials | Alicia Morgans, MD, MPH Dana-Farber Cancer Institute, Boston, MA |
| 12:20 PM | How PCWG4 impacts future trials | Michael Morris, MD Memorial Sloan Kettering, New York, NY |
| 12:30 PM | Approaches to Phase 0/1 Development | Anna Karman, MD, PhD AdvanCell |
| 12:40 PM | Discussion | |
| Developing Novel Radioligands 1 | ||
| 1:10 PM | Review of Phase 1/2 compounds recently published | Jeremie Calais, MD, PhD UCLA |
| 1:20 PM | Struggles with managing radioligand therapy trials | Theranostics Clinical Research Program |
| 1:30 PM | Discussion | |
| Developing Novel Radioligands 2 | ||
| 1:50 PM | Optimization of radioligand chemistry | John Babich, PhD Ratio Therapeutics |
| 2:00 PM | Initial experience with APC3 | Philipp Backhaus, MD University of Münster, Germany |
| 2:10 PM | Does FAP have a future: pro / con |
|
| 2:20 PM | Interactive target session | |
| 2:30 PM | Discussion |
|
| 2:50 PM | BREAK | |
| Wrap-up and Poster Presentations | ||
| 3:20 PM | Wrap-up |
|
| 3:30 PM | Poster Slam | Presenters |
| 4:00 PM | Cocktail hour |